Avanti West Coast from Euston
Best for most- London Euston to Manchester PiccadillyAvanti West Coast runs direct trains several times an hour, and the fastest take about 2 hours. Some stop at Stoke-on-Trent, Macclesfield or Stockport.
- Piccadilly to the marketsWalk about 15 minutes to Albert Square, or take the Metrolink tram from Piccadilly to St Peter's Square or Market Street.
Advance singles can start at around £15–£30 if you book early. Walk-up fares are much higher, so avoid travelling at peak times without a ticket.